Protein viscosity is a major challenge in preparing highly concentrated protein formulations suitable for subcutaneous injection. Highly viscous solutions do not only pose a challenge when administering a drug to a patient, they can also impose technical limitations in the manufacturing process.
This whitepaper evaluates the effect of the excipients in the Viscosity Reduction Platform on ultrafiltration processes used to produce a highly concentrated formulation of a monoclonal antibody.
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