Abzena's process development, optimization and manufacturing teams work together to develop quality, commercially viable processes, that ensure a seamless scaleup directly from bench scale to final manufacturing through to commercialization.
Development capabilities include:
- Experience with multiple mammalian cell types including CHO, ABZCHO K1, sp2/0, yp2/0, and NSO
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Experience beyond mAbs including fabs, ADCs, oligonucleotides, nanoparticles, bispecifics, fusion proteins, vaccines, viruslike particles, enzymes, and bioconjugates
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Transfer verification optimization of your process
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Design of statistical experiments to optimize media feeds and growth conditions
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Scale down fed batch and perfusion production models
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Robotic systems from 250ml to manufacturing scale at 2K
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High cell density and titer optimization
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Bench scale process characterization and validation
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Coordination with inhouse Analytical Method Development (AMD) to determine quality attributes