Customized for your molecule and development phase, Abzena align your drug to your preferred target product profile (TPP) with a comprehensive range of formulation development packages including stable liquid and lyophilized formulations.
We select your best lead candidate through screening of optimal buffer conditions and formulation options to inform successful drug substance manufacturing conditions and drug product forms that support longterm stability.
Our team is experienced in developing formulations for small and large therapeutic molecules such as peptides, proteins, monoclonal antibodies and antibodydrug conjugates (ADCs).
Our stateoftheart laboratories are equipped with the latest analytical equipment and methods to evaluate the integrity of your drug under an array of conditions to inform optimal formulation constituents and forms.
Our capabilities include:
- UHPLC systems
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Biophysical stability assessment platforms and particle size assessment equipment such as Prometheus, UNcle and ZetaSizer Ultra
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Mass spectrometry instruments (TOF MS, QTOF MS)
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Microfluidic platform (LabChip)
What sets our biologics formulation development services apart?
- We have delivered delivered over 1400+ programs, developing formulations for a diverse range of therapeutic modalities
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Fully integrated, comprehensive formulation development support across: mAbs, ADCs, AOCs, Radioconjugates, Bispecifics, Fusion Proteins, Cytokines, Recombinant & Conjugate Vaccines, Nanoparticles and Biosimilars
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Experience of supporting clients with all stages of drug development, from discovery through product launch and subsequent lifecycle management
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Problem solving and applying knowledge to provide productenabling solutions e.g., addressing viscosity or solubility issues
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A number of returning customers emphasize their confidence and trust in our complex biologic development abilities