Our approach focuses on developing phaseappropriate bioassays for assessment of potency, efficacy and safety, giving you insight to make informed decisions during your drug development journey.
We also develop and fully document the phase appropriate analytical methods necessary to produce highquality, wellcharacterized material and the rapid data needed to support successful IND and marketing applications.
For each or both services, your program will benefit from our wealth of knowledge and expertise across a diverse range of modalities including bioconjugates & ADCs, multispecifics, fusions, fragments, agonist, and antagonist activities and more.
Extensive Panel of Target & Effector Cells. To help understand your molecule in detail, we have an extensive panel of both target and effector cells together with a substantial inhouse PBMC cell bank. Complementing this is a broad choice of bioassay platforms including:
- Luminescence, fluorescence, absorbance platebased assays
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BiacoreTM
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Flow cytometry
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Incucyte® live cell imaging (and other microscopy techniques)
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Cytokine analysis (Luminex®, FluoroSpot)
Our comprehensive suite of bioassay solutions includes both established assays and custom assay development matched to your individual program needs. Our bioassay services include:
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Target validation
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Hittolead screening
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Specificity & tissue profiling
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Mode of action
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Immunogenicity & Safety assessment
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Manufacturing – Potency & Batch release